Pablo G Cámara, PhD

Pablo G. Camara, Ph.D. is an Assistant Professor in the Department of Genetics, Perelman School of Medicine, and a member of the Penn Institute for Biomedical Informatics. The research of Dr. Camara utilizes principles of mathematics to address some of the problems that the complexity and scale of current biological data pose to traditional computational methods. Drawing ideas from topology, geometry, statistics, physics, and computer science, and making use of high-throughput single-cell technologies and large-scale population studies, his group aims to achieve a more complete understanding of the cellular composition and signaling networks of tumors in relation to their genetics. The main current research directions of his group include the development of algorithms for the integration and analysis of single-cell multi-omics and imaging data, their application to decipher the cellular ecosystem and oncogenic pathways of brain tumors, and the functional characterization of CAR-T cell immunotherapies in leukemia.